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pde11 is expressed in skeletal muscle, the prostate, the liver, the kidney, the pituitary gland, and the testes. the effects on the body of inhibiting pde11 are not known. tadalafil is an annulated 2, 5- diketopiperazine. a: some cialis ( tadalafil) information, which may be beneficial when considering or beginning treatment, should include reason for use and mechanism of action, proper dosage and administration. these highlights do not include all the information needed to use cialis safely and effectively.


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    this drug is slightly more popular than comparable drugs. tadalafil is a carboline- based compound with vasodilatory activity. tadalafil selectively inhibits the cyclic guanosine monophosphate ( ) - specific type 5 phosphodiesterase- ( pde- 5) - mediated degradation of cgmp, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. cialis® ( tadalafil) : dosing and administration for erectile dysfunction or benign prostatic hyperplasia cialis ( tadalafil) is available for use as needed or for use once daily. regardless of therapy schedule, tadalafil should not be taken more than once per day.
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