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    this drug is slightly more popular than comparable drugs. tadalafil is a carboline- based compound with vasodilatory activity. tadalafil selectively inhibits the cyclic guanosine monophosphate ( ) - specific type 5 phosphodiesterase- ( pde- 5) - mediated degradation of cgmp, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. cialis® ( tadalafil) : dosing and administration for erectile dysfunction or benign prostatic hyperplasia cialis ( tadalafil) is available for use as needed or for use once daily. regardless of therapy schedule, tadalafil should not be taken more than once per day.
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